Priyadarshini Kachroo

Network Analysis Reveals Protein Modules Associated with Childhood Respiratory Diseases

The paper uses WGCNA to identify protein modules in 1-year-old children linked to respiratory diseases by age 6, showing associations with environmental and metabolomic factors.

DNA-methylation markers associated with lung function at birth and childhood reveal early life programming of inflammatory pathways

The paper identifies DNA-methylation markers at birth and childhood associated with lung function and reveals sex- and genetics-related pathways linked to asthma and lung development.

OMICmAge: An integrative multi-omics approach to quantify biological age with electronic medical records

The paper develops OMICmAge, a multi-omics biomarker of biological age, and shows it outperforms existing markers in predicting chronic diseases and mortality.

An exact, unifying framework for region-based association testing in family-based designs, including higher criticism approaches, SKATs, multivariate and burden tests

The paper introduces a framework for region-based association testing in family-based studies, showing improved performance over existing methods in simulations and a real dataset.

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

The paper identifies germline genetic variants associated with clonal hematopoiesis of indeterminate potential (CHIP) using whole genome sequences from the TOPMed program.