Author

Deniz Ghaffari

University of TorontoORCID 0000-0001-5567-9581Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Peter St George‐HyslopiD· 2 shared Alon Rabinovich· 1 shared Alondra Schweizer BurgueteiD· 1 shared Andrey A. BobkoviD· 1 shared Annie LeeiD· 1 shared Badri Narayan VardarajaniD· 1 shared Beatrice Acheson· 1 shared Christopher Böhm· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Peter St George‐HyslopORCID

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2 papers

Recent·Most cited

NeuroscienceDOAJ (DOAJ: Directory of Open Access Journals)Peer-reviewedJul 1, 2026

CD33 and Clusterin Interact Biophysically and Genetically to Modulate Alzheimer Risk

Roger B. Dodd, Masahiro Enomoto, Ye Zhou…·Peter St George‐Hyslop

This study shows how non-coding variants in CD33 affect Alzheimer's risk by altering CD33M dimerization and interactions with clusterin and Aβ, impacting microglial function.

1 citationtop 5%

humanproteomics

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NeurosciencebioRxivPreprintOct 5, 2023

ABI3 deletion in TgCRND8 mice is associated with reduced amyloid plaque pathology and altered glial response.

Deniz Ghaffari, Jennifer K. Griffin, Peter St George‐Hyslop

3 citations

mouseexperimental assay

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