Author

Roger B. Dodd

AstraZeneca (United Kingdom)ORCID 0000-0003-4268-1863Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Alina P. SergeevaiD· 1 shared Alon Rabinovich· 1 shared Alondra Schweizer BurgueteiD· 1 shared Andrew G. BuchananiD· 1 shared Andrey A. BobkoviD· 1 shared Anna SigurdardottiriD· 1 shared Annie LeeiD· 1 shared Badri Narayan VardarajaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Alina P. SergeevaORCID

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2 papers

Recent·Most cited

NeuroscienceDOAJ (DOAJ: Directory of Open Access Journals)Peer-reviewedJul 1, 2026

CD33 and Clusterin Interact Biophysically and Genetically to Modulate Alzheimer Risk

Roger B. Dodd, Masahiro Enomoto, Ye Zhou…·Peter St George‐Hyslop

This study shows how non-coding variants in CD33 affect Alzheimer's risk by altering CD33M dimerization and interactions with clusterin and Aβ, impacting microglial function.

1 citationtop 5%

humanproteomics

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BiophysicsJournal of Molecular BiologyPeer-reviewedApr 24, 2024

Robust prediction of relative binding energies for protein-protein complex mutations using free energy perturbation calculations

Jared M. Sampson, Daniel A. Cannon, Jianxin Duan…·Lingle Wang

The paper benchmarks free energy perturbation calculations for predicting mutation effects on protein-protein binding affinity and introduces an automated method to improve accuracy.

24 citations

protein structuredeep learning

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