David R. Mack

This study identifies elevated paucimannosidic and truncated N-glycans in the microbiota of pediatric ulcerative colitis patients compared to controls, suggesting a potential role for glycan metabolism in disease pathogenesis.

This study quantifies protein-level functional redundancy in the human gut microbiome using ultra-deep metaproteomics and network analysis, revealing high redundancy and environmental influences on functional organization.

The paper uses measured and predicted gene expression to identify ulcerative colitis patients at elevated risk of colectomy, showing both methods independently replicate in multiple datasets.

The paper characterizes lysine acetylation in the human gut microbiome and identifies differential acetylation patterns in Crohn’s disease patients.