Rui Chen

This paper identifies extensive lysine acetylation in bacteriophage proteins during infection, revealing host-driven modifications that affect phage replication and infectivity.

This study uses multi-omic profiling to analyze Caco-2 cell differentiation, showing similar protein and pathway changes in spontaneous and medium-induced differentiation, with butyrate accelerating differentiation and altering protein expression related to host-microbiome interactions.

This study identifies elevated paucimannosidic and truncated N-glycans in the microbiota of pediatric ulcerative colitis patients compared to controls, suggesting a potential role for glycan metabolism in disease pathogenesis.

The paper introduces a chemoenzymatic method to quantitatively analyze N-glycan types on glycoproteins, demonstrating its application in characterizing glycan heterogeneity in IgG1 and MCF7 cells.