Alison A. McBride

This study identifies the lncRNA DINO as a host factor that promotes HPV genome replication and early viral gene expression independently of keratinocyte differentiation.

This study shows that the histone chaperone HIRA and its complex are recruited to HPV replication factories, facilitating viral DNA amplification and transcription.

The paper shows Sp100A promotes HIRA localization to PML-NBs in keratinocytes, with the SUMO interacting motif being critical for this function.

This study shows HPV31 genomes associate with active host chromatin regions, linking viral persistence to transcriptional activity and integration sites in cervical cancers.

This paper uses ANCHOR technology to track HPV18 genomes in live keratinocytes, showing they are randomly partitioned to daughter cells during division.