Gisela Brändén

This study develops a room-temperature serial crystallography workflow for fragment screening of soluble epoxide hydrolase, achieving a 10.4% hit rate with high-quality structures.

The paper introduces a 3D-printed fixed-target platform for macromolecular crystallography that simplifies microcrystal handling and data collection at synchrotrons.

This study explores serial crystallography for drug discovery by determining room-temperature structures of soluble epoxide hydrolase and comparing them to cryo-temperature structures.