Rafael A. Fissore

This study shows that the zinc transporter Zip10 is essential for zinc sparks during fertilization in mice, which are critical for embryo development.

This study identifies a domain-swapped conformation in CaMKII that enables linker-mediated allosteric regulation, demonstrated through structural, computational, and live-cell analyses.

This study shows that Zn2+ is essential for Ca2+ oscillations in mouse eggs, with both insufficient and excessive Zn2+ disrupting these responses.

The paper develops a genetically encoded sensor, FRESCA, for measuring endogenous CaMKII activity, showing it captures aggregate activity across multiple variants unlike existing sensors.

This study shows that simultaneous deletion of TRPV3 and CaV3.2 channels in mice leads to subfertility and impaired Ca2+ homeostasis in oocytes and eggs.