Author

Kairong Dong

University of Massachusetts AmherstORCID 0009-0009-7939-1377Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

Jianhan CheniD· 2 shared Ana P. Torres‐OcampoiD· 1 shared Bao V. NguyeniD· 1 shared Can ÖzdeniD· 1 shared Daniel Flaherty· 1 shared Diana R. TomchickiD· 1 shared Jian An HuangiD· 1 shared Jian Wen HuangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

Jianhan ChenORCID

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2 papers

Recent·Most cited

BiophysicsThe Journal of Physical Chemistry BPeer-reviewedJun 29, 2026

Coupled Binding and Folding of NS2B/NS3 Protease and Linker Effects Revealed by Topology-based Modeling

Kairong Dong, Jian Wen Huang, Min Chen, Jianhan Chen

This paper uses topology-based modeling to study the binding and folding of WNV NS2B/NS3 protease and shows how the G4SG4 linker affects its stability and folding pathways.

1 citation

protein structuredeep learning

𝕏 PostBluesky

BiochemistryNature CommunicationsPeer-reviewedSep 26, 2025

A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation

Bao V. Nguyen, Can Özden, Kairong Dong…·Margaret M. Stratton

This study identifies a domain-swapped conformation in CaMKII that enables linker-mediated allosteric regulation, demonstrated through structural, computational, and live-cell analyses.

5 citations

structural biologyexperimental assay

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