Javier Mancheño-Bonillo

This study shows that bacteriophages use cross-species communication via AimP peptides and AimR receptors to influence lysogeny and prophage induction in mixed microbial cultures.

The paper reveals a DNA recognition-mimicry switch mechanism in SPBeta-like phages where an antirepressor inactivates a repressor via DNA mimicry, enabling lytic induction under SOS conditions and in the absence of neighboring prophages.

This paper engineers a bistable genetic toggle switch in plants using the phage PhiC31 integration system to control gene expression with reversible state changes.