Author

Frank W.G. Leebeek

Erasmus MCORCID 0000-0001-5677-1371Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

András BallaiD· 1 shared Buram Ardic· 1 shared Cristina Xia· 1 shared Dirk SiegeriD· 1 shared Ferenc András AntoniiD· 1 shared Heather McClafferty· 1 shared Isabel BäriD· 1 shared Jan VoorbergiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperEvolutionary Biology

András BallaORCID

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2 papers

Recent·Most cited

Evolutionary BiologyiSciencePeer-reviewedJul 1, 2026

Adenylyl cyclase 9: fundamental change of regulation in vertebrates and gene sub-functionalization after teleost-specific whole-genome duplication

Ferenc András Antoni, Julie Mazzolini, Heather McClafferty…·Paul Skehel

The paper examines the evolution of adenylyl cyclase 9 regulation in vertebrates, showing how teleost-specific whole-genome duplication led to sub-functionalization of adcy9 ohnologs.

1 citation

humanmouse

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Cell BiologybioRxivPreprintApr 3, 2026

A Novel VWF Knockout Endothelial Cell Model to Study Von Willebrand Factor Biology and Von Willebrand Disease Mechanisms

Isabel Bär, Petra E. Bürgisser, Buram Ardic…·Ruben Bierings

The paper introduces a VWF-knockout endothelial cell model to study VWF variants and their impact on von Willebrand disease, showing it can distinguish pathogenic from non-pathogenic variants.

DOI 10.64898/2026.04.01.715845

humanexperimental assay

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