Johannes J. Letzkus

This study shows NDNF interneurons in layer 1 modulate inhibition via GABAergic transmission, controlling information flow in pyramidal cells through competition with SOM interneurons.

This study identifies NDNF-expressing layer 1 interneurons as top-down master regulators of cortical circuits through widespread inhibition of deeper layer interneurons and unique physiological properties.

The paper identifies long-range inhibitory input to layer 1 of the auditory cortex and shows its role in facilitating memory through plasticity during threat learning.