Author

Marcos Castro‐Guarda

University of OxfordORCID 0000-0001-5678-5319Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Anandhakumar Chandran· 1 shared Carolyn A. CarriD· 1 shared Charlotte Daly· 1 shared Christopher M. PalmeriD· 1 shared Claudia N. Montes AparicioiD· 1 shared Francesca Meteora BuffaiD· 1 shared Herman WoloskeriD· 1 shared Javier Gilbert‐JaramilloiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Anandhakumar Chandran

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 11, 2026

Developmental Bioenergetic Reprogramming and Glycolytic Shift in Schizophrenia Vulnerability

Javier Gilbert‐Jaramillo, Oluwarotimi O. Folorunso, Marcos Castro‐Guarda…·Zóltan Sarnyai

This study investigates how early developmental metabolic changes in mouse models relate to schizophrenia vulnerability, finding increased glycolytic activity as a potential convergent mechanism.

DOI 10.64898/2026.05.09.723970

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintNov 20, 2024

Multiomics-based assessment of 2D and 3D human iPSC-cardiomyocyte models of insulin resistance demonstrate metabolic and contractile dysfunction that recapitulates diabetic cardiomyopathy.

Ryan D. Carter, Ujang Purnama, Marcos Castro‐Guarda…·Carolyn A. Carr

The paper uses multiomics analysis of 2D and 3D hiPSC-CMs under insulin resistance conditions to show metabolic and contractile dysfunction resembling diabetic cardiomyopathy.

2 citations

humanbulk RNA-seq

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