PathologybioRxivPreprint
Energetic failure and oxidative stress underlie the Prpf31 splicing factor-related mouse phenotype
Abdallah Hamieh, Elora M. Vanoni, Quentin Rieu…·Emeline F. Nandrot
This study identifies metabolic impairments and oxidative stress in Prpf31 mutant mouse RPE cells as key factors in retinitis pigmentosa pathogenesis.
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