Hui A. Chen

The paper uses cryo-EM to analyze lambda-6 light chain amyloid structures from different organs and patients, revealing structural diversity and potential interactions with collagen-VI.

This paper introduces TEAMKidney, a deep learning framework for automated segmentation and quantification of TEM images, showing improved accuracy and efficiency over existing methods.

The paper reports a cryo-EM structure of cardiac AL-224L amyloid and identifies shared structural features across {lambda}6-LC amyloid folds.

This paper develops a deep learning method to automate measurement of glomerular basement membrane and podocyte foot process widths in TEM images of podocytopathy mouse models, showing comparable accuracy to manual methods.