Olga Gursky

The paper uses cryo-EM to analyze lambda-6 light chain amyloid structures from different organs and patients, revealing structural diversity and potential interactions with collagen-VI.

This study identifies small molecules that stabilize diverse amyloidogenic immunoglobulin light chains by reducing conformational dynamics and proteolysis.

The paper reports a cryo-EM structure of cardiac AL-224L amyloid and identifies shared structural features across {lambda}6-LC amyloid folds.

The paper identifies a novel form of hereditary apoA-I amyloidosis caused by Glu34Lys mutation, revealing structural changes that lead to amyloid formation and vision loss.