Author

Jingyi Hu

Ruhr University BochumORCID 0000-0001-5734-1111Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1

Frequent Co-Authors

Frank SchulziD· 2 shared Marius Brandenburger· 2 shared Susanna Kushnir· 2 shared Sofia Camila BravoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBiochemistry

Frank SchulzORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 26, 2025

In Vivo Mutagenesis of a Ketosynthase Domain Uncovers Productivity and Specificity Control in Modular Polyketide Synthases

Jingyi Hu, Susanna Kushnir, Marius Brandenburger, Frank Schulz

The paper identifies active-site motifs in a ketosynthase domain that control productivity and specificity in polyketide synthases through in vivo mutagenesis and structural analysis.

DOI 10.1101/2025.09.26.678738

experimental assaychromatin & epigenetic regulation

𝕏 PostBluesky

BiochemistrybioRxivPreprintSep 16, 2025

Overcoming Biosynthetic Limitations to Enhance Bacterial Polyketide Production

Sofia Camila Bravo, Jingyi Hu, Susanna Kushnir…·Frank Schulz

This study enhances bacterial polyketide production by optimizing medium composition and engineering enzymes, showing medium optimization is more effective than enzyme mutation.

1 citation

bacteria (other)metabolomics

𝕏 PostBluesky