Author

Tingting Wu

Washington University in St. LouisORCID 0000-0001-5736-4962Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 3 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Matthew D. LewiD· 3 shared Daoyuan QianiD· 1 shared David A. WeitziD· 1 shared Gaurav ChauhaniD· 1 shared Hannes AusserwögeriD· 1 shared Jin LüiD· 1 shared Md Ashequr RahmaniD· 1 shared Mina FaragiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMolecular Biology

Matthew D. LewORCID

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3 papers

Recent·Most cited

BiophysicsNature CommunicationsPeer-reviewedApr 11, 2025

Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates

Nadia A. Erkamp, Mina Farag, Yuanxin Qiu…·Rohit V. Pappu

The paper investigates anisotropies in RNA-based biomolecular condensate interfaces, finding that purine-rich RNAs drive phase separation while pyrimidine-rich RNAs accumulate at interfaces, with distinct motion patterns observed using single-molecule imaging.

34 citationstop 1%

imagingmicroscopy & imaging analysis

𝕏 PostBluesky

Molecular BiologyOptics ExpressPeer-reviewedSep 12, 2022

Deep-SMOLM: Deep Learning Resolves the 3D Orientations and 2D Positions of Overlapping Single Molecules with Optimal Nanoscale Resolution

Tingting Wu, Peng Lu, Md Ashequr Rahman…·Matthew D. Lew

Deep-SMOLM improves 3D orientation and 2D position measurement of overlapping single molecules with high precision and speed.

22 citations

imagingdeep learning

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Molecular BiologyOpticaPeer-reviewedApr 5, 2022

pixOL: pixel-wise dipole-spread function engineering for simultaneously measuring the 3D orientation and 3D localization of dipole-like emitters

Tingting Wu, Jin Lü, Matthew D. Lew

The paper introduces pixOL, a method that improves the precision of measuring 3D orientation and localization of fluorescent molecules using engineered dipole-spread functions.

44 citationstop 4%

imagingexperimental assay

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