Soren M. Gantt

KmerSignificance Score (KSS) prioritizes viral k-mers by integrating strain-distinguishing capacity, mutation impact, and functional importance, achieving superior classification performance and cross-dataset comparability.

This study investigates the spatial kinetics and immune control of murine cytomegalovirus infection in salivary glands, identifying immune correlates and constructing mathematical models to understand viral spread and control.

KEVOLVE identifies SARS-CoV-2 variant-specific genomic signatures using machine learning, outperforming statistical tools and highlighting biologically relevant mutations.

The paper shows that HIV-positive mothers have compartmentalized CMV genotypes, with three infants transmitting a single closely related maternal cervix strain, and identifies gene similarities linked to tissue-tropism and immunomodulation.