Juanita Pang

Mixed cytomegalovirus genotypes in HIV positive mothers show compartmentalization and distinct patterns of transmission to infants.

The paper shows that HIV-positive mothers have compartmentalized CMV genotypes, with three infants transmitting a single closely related maternal cervix strain, and identifies gene similarities linked to tissue-tropism and immunomodulation.

Detection of a historic reservoir of bedaquiline / clofazimine resistance associated variants in Mycobacterium tuberculosis

The paper identifies pre-existing bedaquiline resistance variants in Mycobacterium tuberculosis genomes before clinical use of the drug, highlighting the need for rapid susceptibility testing.

Haplotype assignment of longitudinal viral deep-sequencing data using co-variation of variant frequencies

This paper introduces HaROLD, a method for haplotype reconstruction from longitudinal viral sequencing data using co-varying variant frequencies, showing high accuracy with synthetic datasets.