Author

Pauline M. Bennett

King's College LondonORCID 0000-0001-5754-0081Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:proteomics· 1 Organism:zebrafish· 1

Frequent Co-Authors

Mathias GauteliD· 2 shared Melissa A. B. AmerudiniD· 2 shared Yaniv HinitsiD· 2 shared Ailbhe O Brien· 1 shared Alicia Cuber CaballeroiD· 1 shared Andrew J. BeaviliD· 1 shared Ay Lin KhoiD· 1 shared Celine F. SantiagoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

Mathias GautelORCID

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2 papers

Recent·Most cited

BioengineeringCommunications BiologyPeer-reviewedSep 23, 2026

The generation and validation of a de novo-designed titin binder for use in fluorescence microscopy

Martin Rees, Andrew J. Beavil, Melissa A. B. Amerudin…·Mathias Gautel

The paper designs and validates a de novo protein binder for the titin M10 domain, demonstrating its utility in fluorescence microscopy without antibodies.

DOI 10.1038/s42003-026-10988-1

humanproteomics

𝕏 PostBluesky

Cell BiologyCirculation ResearchPeer-reviewedJan 7, 2026

Location-Dependent Differences in Cardiac and Skeletal Muscle Dysfunction Associated With Truncating Titin (ttn.2) Variants

Celine F. Santiago, Inken G. Huttner, Ailbhe O Brien…·Yaniv Hinits

This study investigates how truncating variants in the ttn.2 gene affect cardiac and skeletal muscle function in zebrafish, showing location-specific differences in disease severity and phenotypes.

DOI 10.1161/circresaha.124.325999

zebrafishexperimental assay

𝕏 PostBluesky