BioinformaticsCellular and Molecular Life SciencesPeer-reviewed
Inhibiting a promiscuous GPCR: iterative discovery of bitter taste receptor ligands
Fabrizio Fierro, Lior Peri, Harald Hübner…·Masha Y. Niv
The paper discovers new ligands for the promiscuous TAS2R14 bitter taste receptor using a mixed experimental and computational approach, identifying 10 antagonists and 200 agonists.
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