Author
Friedrich-Alexander-Universität Erlangen-NürnbergORCID 0000-0003-2259-9002Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Jun Zhi Xu, Ruoyi Qiu, Alexander M. Garces…·Brian K. Kobilka
This study uses single-molecule imaging to show how agonist-specific dynamics in structured and disordered regions of the 2AAR regulate signaling and function.
Lior Peri, Donna Matzov, Dominic R. Huxley…·Moran Shalev-Benami
The paper reveals the cryo-EM structure of hTAS2R14 bound to FFA and gustducin, showing dual binding pockets and supporting a dual binding mode for FFA.
Fabrizio Fierro, Lior Peri, Harald Hübner…·Masha Y. Niv
The paper discovers new ligands for the promiscuous TAS2R14 bitter taste receptor using a mixed experimental and computational approach, identifying 10 antagonists and 200 agonists.