Author

Arran Hodgkinson

Centre National de la Recherche ScientifiqueORCID 0000-0001-5810-0168Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Ovidiu RadulescuiD· 2 shared Dumitru TrucuiD· 1 shared Guilherme C. P. InnocentiniiD· 1 shared Laurent Le CamiD· 1 shared Matthieu LacroixiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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2 shared papersSystems Biology

Ovidiu RadulescuORCID

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2 papers

Recent·Most cited

Systems BiologyFrontiers in OncologyPeer-reviewedApr 14, 2022

Computational Model of Heterogeneity in Melanoma: Designing Therapies and Predicting Outcomes

Arran Hodgkinson, Dumitru Trucu, Matthieu Lacroix…·Ovidiu Radulescu

This paper develops a computational model to predict outcomes of different therapeutic strategies in melanoma by analyzing single-cell mRNA sequencing data and simulating tumor heterogeneity and drug resistance.

8 citations

humanbulk RNA-seq

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Systems BiologyFrontiers in PhysicsPeer-reviewedJun 8, 2018

Time Dependent Stochastic mRNA and Protein Synthesis in Piecewise-deterministic Models of Gene Networks.

Guilherme C. P. Innocentini, Arran Hodgkinson, Ovidiu Radulescu

The paper develops piecewise-deterministic models to approximate gene network dynamics and evaluates methods for computing time-dependent stochastic distributions of mRNA and protein synthesis.

11 citations

statistical model

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