Author

Dumitru Trucu

University of DundeeORCID 0000-0003-4390-7537Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ali DaheriD· 1 shared Arran HodgkinsoniD· 1 shared Laurent Le CamiD· 1 shared Matthieu LacroixiD· 1 shared Ovidiu RadulescuiD· 1 shared Raluca EftimieiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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1 shared paperSystems Biology

Ali DaherORCID

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2 papers

Recent·Most cited

Systems Biologynpj Systems Biology and ApplicationsPeer-reviewedFeb 19, 2026

A Computational Pipeline for Physiologically Informed Calibration of Ligand Reaction-Diffusion Models Using High-Throughput Sequencing

Ali Daher, Dumitru Trucu, Raluca Eftimie

The paper develops a computational pipeline to calibrate reaction-diffusion models of ligand signaling using transcriptomics data, applied to TGF{beta} isoforms in wound healing.

2 citations

humanscRNA-seq

𝕏 PostBluesky

Systems BiologyFrontiers in OncologyPeer-reviewedApr 14, 2022

Computational Model of Heterogeneity in Melanoma: Designing Therapies and Predicting Outcomes

Arran Hodgkinson, Dumitru Trucu, Matthieu Lacroix…·Ovidiu Radulescu

This paper develops a computational model to predict outcomes of different therapeutic strategies in melanoma by analyzing single-cell mRNA sequencing data and simulating tumor heterogeneity and drug resistance.

8 citations

humanbulk RNA-seq

𝕏 PostBluesky