Author

Patrick Krohn

University of ZurichORCID 0000-0001-5821-9919Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

Alessandro LucianiiD· 1 shared Olivier DevuystiD· 1 shared Svenja Aline KelleriD· 1 shared Zhiyong CheniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperPathology

Alessandro LucianiORCID

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1 paper

Recent·Most cited

PathologybioRxivPreprintFeb 3, 2026

SGLT2 Inhibitors Rescue Lysosomal mTORC1 Hyperactivity and Proximal Tubulopathy in Preclinical Models of Cystinosis

Svenja Aline Keller, Patrick Krohn, Zhiyong Chen…·Olivier Devuyst

This study shows SGLT2 inhibitors reduce mTORC1 hyperactivity and proximal tubulopathy in cystinosis models by altering lysosomal metabolism, independent of cystine clearance.

DOI 10.64898/2026.01.29.702541

zebrafishmouse

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