BiophysicsProceedings of the National Academy of SciencesPeer-reviewed
Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility
Ankit Garg, Silvia Jansen, Lina Greenberg…·Michael J. Greenberg
This study shows that the ACTA1 R256H mutation disrupts actin structure and function in cardiomyocytes, leading to reduced contractility and a likely causative role in dilated cardiomyopathy.
19 citationstop 3%