NeuroscienceJournal of Parkinson s DiseasePeer-reviewed
Antisense oligonucleotides targeting alpha-synuclein reduce pre-formed fibril-induced Lewy pathology and improve some domains of cognitive and motor performance
Sydney Weber Boutros, Jacob Raber, Vivek K. Unni
This study shows that antisense oligonucleotides targeting alpha-synuclein reduce Lewy body pathology and improve cognitive and motor performance in a mouse model of synucleinopathy.
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