Author

Maddie R. Lemieux

University of Colorado BoulderORCID 0000-0001-5875-9579Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Christopher D. LinkiD· 2 shared Alyssa N. CavalieriD· 1 shared Bernhard Freigassner· 1 shared Charles A. HoefferiD· 1 shared Christine M. RobertsiD· 1 shared Jessica L. HansoniD· 1 shared Mark R. OppiD· 1 shared Micklaus A. Garcia· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Christopher D. LinkORCID

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2 papers

Recent·Most cited

Multielectrode array characterization of human induced pluripotent stem cell derived neurons in co-culture with primary human astrocytes.

Maddie R. Lemieux, Bernhard Freigassner, Jessica L. Hanson, Zahra Thathey, Mark R. Opp, Charles A. Hoeffer, Christopher D. Link

This study characterizes human induced pluripotent stem cell-derived neurons co-cultured with astrocytes using MEAs, achieving strong network synchrony in six weeks.

PLoS ONE · Jun 25, 2024Peer-reviewedNeuroscience

Amyloid beta acts synergistically as a pro-inflammatory cytokine

Thomas J. LaRocca, Alyssa N. Cavalier, Christine M. Roberts, Maddie R. Lemieux, Pooja Ramesh, Micklaus A. Garcia, Christopher D. Link

This study shows that amyloid beta acts as a pro-inflammatory cytokine by synergizing with other cytokines to activate astrocytes in a manner distinct from high-dose effects.

Neurobiology of Disease · Aug 28, 2021Peer-reviewedMolecular Biology