Lindsay A. Welikovitch

This study shows that Mbd2 deficiency in mice leads to cognitive and social deficits, altered gene expression, and DNA methylation patterns similar to those in ASD, suggesting Mbd2 is an epigenetic regulator of ASD-risk genes.

The paper compares the bioactivity of fibrillar and oligomeric tau forms in Alzheimer's disease, finding HMW tau more potent in glial activation and tau propagation.

This study uses single-nucleus RNA-sequencing to analyze astrocyte transcriptomic changes across the spatiotemporal progression of Alzheimer's disease, revealing gene expression trajectories and heterogeneity.