Biophysicsnpj VirusesPeer-reviewed
Structural Dynamics of the Dengue Virus Non-structural 5 (NS5) Interactions with Promoter Stem Loop A (SLA)
Juliet O. Obi, Kyle C. Kihn, Linfah McQueen…·Daniel Joseph Deredge
This study investigates the structural dynamics of DENV2 NS5 interacting with SLA using SPR, HDX-MS, computational modeling, and cryoEM, revealing conformational changes and a conserved binding mode.
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