Daniela Digles

The paper creates a functional landscape of human solute carriers by integrating multi-omics data and curated knowledge, assigning functions to each SLC and providing a web-accessible resource.

The paper identifies mutation hotspots in SLC6 transporters linked to clinical pathogenicity by analyzing protein-protein interactions and structural data.

The paper uses proteochemometric modeling to identify amino acids critical for GABA transporter subtype selectivity.