Calum Johnston

This study identifies RumC1 as a broad-spectrum bacteriocin targeting a transient peptidoglycan intermediate in cell wall maturation, with distinct mechanisms from vancomycin.

This study identifies a tripartite protein complex essential for ssDNA uptake during natural transformation in firmicutes, validated through structural modeling and experimental assays.

This study shows that competence-induced expression of RecA and RadA in Streptococcus pneumoniae enhances tolerance to genotoxic stress, highlighting competence as a stress-sensing mechanism.

This study reveals a populational QS mechanism in Streptococcus pneumoniae that drives antibiotic response heterogeneity through competence-induced bet-hedging.