Cell BiologybioRxivPreprint
An NHEJ-independent Role for DNA-PKcs in ATR activation at DNA Double-Strand Breaks
Oanh Huynh, W. Matthew Michael
This paper shows DNA-PKcs phosphorylates TOPBP1 at S1131 to activate ATR at DSBs independently of ATM and NHEJ.
DOI 10.64898/2026.06.19.733426