Meishar Shahoha

ConvergeCELL translates patient transcriptomics into therapeutic hypotheses by integrating patient representation, interpretability, and large language models, outperforming baselines in gene recovery and classification.

This study shows that RapGEF2 is required for cAMP-dependent ERK activation and synaptic potentiation in hippocampus, linking it to context-dependent fear conditioning and cognitive processes.