Sebastian Bauer

This study identifies TRIM11 as a regulator of EWSR1::ATF1 stability in clear cell sarcoma, showing its depletion leads to metabolic rewiring and cell death, with PCK1 as a potential biomarker.

This study uses pan-cancer phosphoproteomics to identify therapeutic targets and improve precision oncology by analyzing 1,998 tumor samples and developing new scores for kinase activity and immune response.

The paper identifies genomic and transcriptomic features of telomere maintenance mechanisms in complex karyotype sarcomas, linking ALT status to therapeutic vulnerabilities.

BARMIX quantifies treatment resistance in gastrointestinal stromal tumor cell mixtures using barcoded experiments and probabilistic modeling, accurately reflecting clinical resistance patterns.

This paper develops dual-color expansion microscopy using non-canonical amino acid labeling to achieve high-resolution imaging of membrane proteins in HEK 293T cells.

This study identifies 6S RNA's role in enhancing virulence gene expression in Yersinia pseudotuberculosis during intestinal colonization.