Author

Martin Del Castillo Velasco‐Herrera

Wellcome Sanger InstituteORCID 0000-0001-5956-0211Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:simulation· 1 Research Focus:variant calling· 1

Frequent Co-Authors

David J. AdamsiD· 2 shared Alastair DroopiD· 1 shared Albrecht StenzingeriD· 1 shared Alvis BrāzmaiD· 1 shared Andrea CiolfiiD· 1 shared Antonella LauriiD· 1 shared Carolin MogleriD· 1 shared Clara AlsinetiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

David J. AdamsORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedMay 19, 2025

✦ In-depth digest

Activation of Wnt/β-catenin signalling by mutually exclusive FBXW11 and CTNNB1 hotspot mutations drives salivary gland basal cell adenoma

Kim Wong, Justin A. Bishop, Ilan Weinreb…·David J. Adams

Exome and transcriptome sequencing of salivary basal cell adenomas reveals a recurrent FBXW11 p.F517S mutation, exclusive with CTNNB1 p.I35T, together accounting for 94% of cases.

15 citationstop 1%

humanwhole-exome sequencing

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Systems BiologyCell ReportsPeer-reviewedAug 1, 2017

Genomic determinants of protein abundance variation in colorectal cancer cells

Theodoros I. Roumeliotis, Steven P. Williams, Emanuel Gonçalves…·Jyoti Sharma Choudhary

The paper quantifies proteomic and genomic variation in colorectal cancer cell lines to understand how mutations affect protein levels and drug responses.

115 citationstop 2%

humanproteomics

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