Alastair Droop

This study investigates the transcriptional responses of yeast to glucose deprivation, identifying roles for Snf12 and Spt20 in metabolic adaptation and stress signaling.

A 3D-printed OpenFlexure Microscope adapted for humid incubators, with relocated electronics, ASA printing and 22 Ω current-limiting resistors, records 48-hour label-free docetaxel responses that CellPhe can analyse.

The paper uses spatial profiling to analyze cellular marker changes in murine brain metastases, identifying upregulated immune markers and downregulated neuronal markers.

This study maps parasite dissemination patterns in visceral leishmaniasis using a barcoded library and ecological analysis, revealing bi-directional highways and super-seeder tissues.

This study identifies the COG complex as essential for Ktd1 trafficking, which mediates resistance to the A/B toxin K28 in yeast.

Exome and transcriptome sequencing of salivary basal cell adenomas reveals a recurrent FBXW11 p.F517S mutation, exclusive with CTNNB1 p.I35T, together accounting for 94% of cases.

The paper generates patient-specific retinal organoids and RPE from RP type 11 patients to show PRPF31 mutations cause retinal-specific splicing defects and structural/functional impairments, which are corrected by in situ gene editing.