Hans J. C. T. Wessels

This study integrates proteomics and functional data using topological analysis to reveal how opposite inotropic drugs affect engineered cardiac tissue.

The paper presents a comprehensive multi-omics dataset of healthy individuals, revealing sex and age influences and providing reference ranges for omics features.

The paper generates a proteogenomic atlas of the human neural retina using long-read RNA-sequencing and mass spectrometry, identifying novel transcript isoforms and peptides.

The paper develops an optimized PASEF workflow for glycoproteomics, significantly increasing N-glycopeptide identifications in human plasma.

The paper develops a plasma N-glycoproteomics method to identify high-specificity disease biomarkers by detecting site-specific glycosylation abnormalities in genetic diseases.

The paper introduces GlycoPaSER, a real-time glycopeptide identification tool that decomposes spectra and uses specialized algorithms for real-time analysis, matching performance with existing software.