Jiayan Zhou

The paper shows FOXP1 and FOXP4 maintain the peripheral Treg pool by regulating chromatin structure at the Il2ra locus to sustain CD25 expression.

This study identifies plasma proteomic signatures that modestly improve prediction of incident type 2 diabetes compared to clinical and genetic factors.

The paper identifies CXCL12 as a genetic driver of coronary artery anatomy variation through GWAS and mouse models, showing its role in fetal coronary development.

This paper develops a plasma proteomic signature for predicting atherosclerotic cardiovascular disease risk using UK Biobank data and finds it modestly improves prediction over clinical and genetic factors.

This paper introduces EDGE, a method to detect nonadditive genetic effects in GWAS, finding nonadditive patterns in over 52% of significant loci for coronary artery disease and body mass index.