Molecular BiologyNucleic Acids ResearchPeer-reviewed
Double-stranded RNA drives SARS-CoV-2 nucleocapsid protein to undergo phase separation at specific temperatures
Christine Roden, Yifan Dai, Catherine A. Giannetti…·Amy S. Gladfelter
This study shows that SARS-CoV-2 N-protein uses two distinct RNA motifs, both requiring dsRNA, to drive phase separation at specific temperatures, enabling multiple viral functions.
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