Yifan Dai

This study shows that redox surveillance in stress granules prevents TDP-43 aggregation by maintaining a controlled redox environment.

The paper shows that alpha-synuclein phase separation can form Lewy body-like structures without pre-existing seeds, suggesting a new mechanism for neurodegeneration.

This paper shows antibiotic condensates activate magnesium signaling to enhance bacterial survival and drug tolerance.

This study shows molecular asymmetry and sequence architecture encode electric potential profiles in biomolecular condensates, revealing how charge distribution and protein structure influence interfacial potentials.

The paper discovers that intrinsically disordered proteins form condensates with catalytic activity through sequence-dependent electrochemical microenvironments, enabling hydrolysis reactions and gene circuit activation in cells.

This study shows that hydrophobic asymmetry in non-charged protein condensates creates electric potential gradients, enabling potential-dependent chemistry.

This study identifies pathway-dependent molecular interactions that define distinct physicochemical properties of biomolecular condensates formed by the same IDP.

The paper shows that biomolecular condensates generate interphase electric potentials due to ion asymmetry, suggesting they function as mesoscale capacitors.

The paper identifies GvpU as the protein governing gas vesicle clustering and shows how its phase transition behavior modulates cellular fitness and clustering states.

This study shows that SARS-CoV-2 N-protein uses two distinct RNA motifs, both requiring dsRNA, to drive phase separation at specific temperatures, enabling multiple viral functions.