Mark Alan Little

This study identifies increased glycolysis in SLE neutrophil subsets, correlating with disease activity and metabolic flexibility.

This study identifies mitochondrial bioenergetic failure in SLE immunocytes, showing reduced OXPHOS across multiple immune subsets and proposes targeting mitochondrial fitness for therapy.

This study identifies genetic subsets of EGPA associated with asthma and eosinophil levels, revealing two distinct clinical and genetic syndromes.