Anjali S Yennemadi

SLE Monocyte Subsets Are Pro-Inflammatory and Display Dysregulated Metabolism in Response to Bacterial Stimuli

This study examines SLE monocyte subsets, finding they are pro-inflammatory and show dysregulated metabolism in response to bacterial stimuli.

Neutrophil subsets in SLE exhibit increased glycolysis that correlates with disease activity

This study identifies increased glycolysis in SLE neutrophil subsets, correlating with disease activity and metabolic flexibility.

HIV inhibits Warburg metabolism in human macrophages infected with Mycobacterium tuberculosis.

This study shows HIV-1 infection suppresses Mtb-induced glycolytic reprogramming in macrophages, altering immunometabolic responses and increasing TB susceptibility.

Human macrophages secrete both interferon α and interferon β protein during infection with Mycobacterium tuberculosis.

This study shows human macrophages secrete both interferon α and β during Mtb infection, challenging previous assumptions about their kinetics and timing.

Sex-Specific Metabolic Programming in Human Neutrophil Subsets

This study identifies sex-specific metabolic differences in human neutrophil subsets, showing male low-density neutrophils have higher oxidative and glycolytic activity compared to female counterparts, independent of maturity.

Mitochondrial Bioenergetic Failure in SLE Immunocytes: Targeting Fitness for Therapy

This study identifies mitochondrial bioenergetic failure in SLE immunocytes, showing reduced OXPHOS across multiple immune subsets and proposes targeting mitochondrial fitness for therapy.

Dexamethasone impairs glycolysis but improves mycobacterial killing in primary human macrophages

This study shows dexamethasone reduces glycolysis in human macrophages but enhances mycobacterial killing, suggesting a potential therapeutic benefit in tuberculosis.