Ganiraju C. Manyam

This paper shows that combining intravesical IFN gene therapy with oral Afatinib improves survival in mice with bladder cancer by targeting the ErbB resistance pathway.

This study identifies adaptive stress response (ASR) signatures in inflammatory breast cancer (IBC) that correlate with tumor emboli survival, dissemination, and therapeutic response.

OmicPioneer-sc provides an interactive visualization tool for single-cell sequencing data, integrating dimensionality reduction, heat maps, and pathway modules to aid in cell-type annotation and multi-omic analysis.

The paper introduces a method to construct gene-specific methylation profiles for integrative methylation-expression analysis in cancer, showing improved explanation of expression variability and identification of methylation differences across cancer subtypes.