Author

Adewunmi Adelaja

University of California, Los AngelesORCID 0000-0001-6010-5072Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alexander HoffmanniD· 2 shared Apeksha SinghiD· 1 shared Brooks E. Taylor· 1 shared Katherine M. SheuiD· 1 shared Michael Iter· 1 shared Quen J. ChengiD· 1 shared Roberto SpreaficoiD· 1 shared Sho OhtaiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSystems Biology

Alexander HoffmannORCID

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2 papers

Recent·Most cited

Systems BiologyCell SystemsPeer-reviewedJun 1, 2024

Stimulus-Response signaling dynamics characterize macrophage polarization states

Apeksha Singh, Supriya Sen, Michael Iter…·Alexander Hoffmann

This study characterizes macrophage polarization states by analyzing NFκB signaling dynamics in response to different stimuli, revealing a multi-dimensional polarization landscape rather than a simple M1/M2 dichotomy.

26 citations

mousescRNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintFeb 18, 2020

NFκB dynamics determine stimulus-responsive epigenomic reprogramming in macrophages

Quen J. Cheng, Sho Ohta, Katherine M. Sheu…·Alexander Hoffmann

This study shows that NFκB activity dynamics determine stimulus-specific epigenomic reprogramming in macrophages by promoting de novo enhancer formation.

11 citations

humanATAC-seq

𝕏 PostBluesky