Author

Brooks E. Taylor

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander HoffmanniD· 2 shared Adewunmi AdelajaiD· 1 shared Katherine M. SheuiD· 1 shared Kyle M. KovaryiD· 1 shared Marie Oliver MetzigiD· 1 shared Mary N. TerueliD· 1 shared Michael L. ZhaoiD· 1 shared Quen J. ChengiD· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersSystems Biology

Alexander HoffmannORCID

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Author profile →

3 papers

Recent·Most cited

An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF-induced necroptosis decisions

Marie Oliver Metzig, Ying Tang, Simon A. Mitchell, Brooks E. Taylor, Robert Foreman, Roy Wollman, Alexander Hoffmann

The paper identifies an incoherent feedforward loop involving NFκB/RelA and A20 that determines TNF-induced necroptosis decisions based on dynamic signaling.

Molecular Systems Biology · Dec 1, 2020Peer-reviewedSystems Biology

NFκB dynamics determine stimulus-responsive epigenomic reprogramming in macrophages

Quen J. Cheng, Sho Ohta, Katherine M. Sheu, Roberto Spreafico, Adewunmi Adelaja, Brooks E. Taylor, Alexander Hoffmann

This study shows that NFκB activity dynamics determine stimulus-specific epigenomic reprogramming in macrophages by promoting de novo enhancer formation.

bioRxiv · Feb 18, 2020 · PreprintMolecular Biology

Expression variation and covariation impair analog and enable binary signaling control

Kyle M. Kovary, Brooks E. Taylor, Michael L. Zhao, Mary N. Teruel

The paper measures protein expression variability in Xenopus laevis and human cells, showing lower variation than expected and demonstrating how covariation between MEK and ERK improves population-level control of binary cell-fate decisions.

Molecular Systems Biology · May 1, 2018Peer-reviewedSystems Biology