Author

Apeksha Singh

University of California, Los AngelesORCID 0000-0001-6523-0614Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander HoffmanniD· 2 shared Adewunmi AdelajaiD· 1 shared David Mastro· 1 shared Dennis J. ChiaiD· 1 shared Dinesh S. RaoiD· 1 shared Jennifer K. KingiD· 1 shared Michael Iter· 1 shared Noa PopkoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Alexander HoffmannORCID

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2 papers

Recent·Most cited

ImmunologyCell ReportsPeer-reviewedAug 26, 2025

Distinct causes of three phenotypic hallmarks of hematopoietic aging

Dennis J. Chia, Apeksha Singh, Yusheng Lin…·Alexander Hoffmann

This study identifies distinct causes for three hematopoietic aging phenotypes using mouse models and single-cell analysis, showing HSC accumulation is NFκB-independent, functional impairment is HSC-autonomous NFκB-driven, and myeloid bias is driven by the NFκB-altered bone marrow environment.

9 citationstop 3%

mousescRNA-seq

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Systems BiologyCell SystemsPeer-reviewedJun 1, 2024

Stimulus-Response signaling dynamics characterize macrophage polarization states

Apeksha Singh, Supriya Sen, Michael Iter…·Alexander Hoffmann

This study characterizes macrophage polarization states by analyzing NFκB signaling dynamics in response to different stimuli, revealing a multi-dimensional polarization landscape rather than a simple M1/M2 dichotomy.

26 citations

mousescRNA-seq

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