Author

Jackson Sheppard

University of California, Santa BarbaraORCID 0000-0001-6018-6108Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:electronic health records· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Brad D. PriceiD· 2 shared Joan‐Emma SheaiD· 2 shared Mark S. SherwiniD· 2 shared Shiny MaityiD· 2 shared Songi HaniD· 2 shared Antonín SojkaiD· 1 shared Bruce A. JohnsoniD· 1 shared Chung-Ta HaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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10 top collaborators · 41 mutual co-author links

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2 shared papersBiophysics

Brad D. PriceORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJul 22, 2026

Reconstructing time-resolved inter-residue distance distributions in a protein ensemble during functional dynamics in solution

Brad D. Price, Jackson Sheppard, Shiny Maity…·Mark S. Sherwin

This paper develops a method to reconstruct time-resolved inter-residue distance distributions in proteins during functional dynamics using rs-TiGGER spectra and applies it to AsLOV2.

DOI 10.64898/2026.07.22.739050

electronic health recordsstatistical model

𝕏 PostBluesky

BiophysicsbioRxivPreprintJun 19, 2025

Hydraulic Activation of the AsLOV2 Photoreceptor

Shiny Maity, Jackson Sheppard, Hannah Russell…·Songi Han

This study shows blue light or high pressure activates AsLOV2 by expelling structured water, causing conformational changes and suggesting hydration water drives protein mechanics.

2 citations

experimental assay

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