An efficient and stable ascorbate/O2-driven route for L-DOPA synthesis by heme-dependent tyrosine hydroxylase
Langxing Liao, Zongyu Bao, Zhihui Jiang…·Binju Wang
This paper demonstrates that heme-dependent tyrosine hydroxylase can efficiently synthesize L-DOPA using ascorbate/O2 instead of H2O2, achieving high conversion rates and stability.